The Yséline Pharmacopoeia

Nature's logic, explained

Every plant in a Yséline formula has been used for centuries and studied by science. We believe you deserve to know exactly what you are putting on your skin — and why it works.

Five botanicals

Ingredients with a story

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Trầu Không

Piper betle · Vietnam Highlands

Rich in eugenol and hydroxychavicol — natural antimicrobial agents used in Indochina for 2,000+ years. Targets acne-causing bacteria without disrupting the skin microbiome. Paired with Niacinamide (N°01) and Zinc PCA (N°02).

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Húng Chanh

Coleus amboinicus · Mekong Delta

Contains carvacrol and thymol — anti-inflammatory and antimicrobial essential oils. Paired with Panthenol B5 (N°03) for a complete barrier-repair formula with zero irritation risk across all skin types.

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Khổ Qua

Momordica charantia · Đà Lạt Plateau

Bitter melon extract shows emerging anti-inflammatory and cytokine-inhibiting activity. Paired with Azelaic Acid 10% (N°04) — FDA-approved for acne and rosacea, with strong clinical evidence for pigmentation.

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Cỏ Mực

Eclipta prostrata · Indochina Wetlands

False daisy extract contains wedelolactone — studied for cellular recovery and melanin regulation. Paired with a 5-Peptide Complex (N°05) for collagen signalling and firming benefit.

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Diếp Cá

Houttuynia cordata · Mekong Delta

Fish mint is packed with quercetin and kaempferol — potent antioxidants that calm inflammation, strengthen the skin barrier, and protect against environmental damage. Used as supporting active across the collection.

The Other Half

The modern actives

Each botanical is paired with a clinically validated active chosen for evidence strength and synergy.

Niacinamide 5%

Vitamin B3 · N°01

Inhibits melanosome transfer, reduces sebum, strengthens the skin barrier. One of skincare's most studied and versatile actives.

Zinc PCA 2%

Zinc pyrrolidone carboxylate · N°02

Inhibits 5-alpha reductase, blocking androgen-driven excess sebum at its hormonal source. Measurable results within 4 weeks.

Panthenol B5 3%

Provitamin B5 · N°03

Converts to pantothenic acid in the skin, accelerating barrier repair. Zero irritation risk across all skin types — the gentlest active in the collection.

Azelaic Acid 10%

Dicarboxylic acid · N°04

FDA-approved for rosacea. Kills acne bacteria, inhibits tyrosinase (melanin synthesis), and reduces keratinocyte proliferation inside follicles.

Peptide Complex

Matrixyl 3000 + Argireline · N°05

Signal peptides upregulate collagen I, III, and fibronectin synthesis. Argireline moderates microcontractions that deepen expression lines.

Find your formula

Science and nature, made for your skin

Every ingredient you just read about is inside one of our five masks.

Shop the Collection